Epsilon Delivers End-to-End Spray Drying Solution for UK CDMO

A leading UK CDMO planned to introduce pharmaceutical spray drying into an existing OSD manufacturing facility. Whilst spray drying appears straightforward, it is one of the most technically demanding pharmaceutical unit operations to design, scale and operate consistently with high product yield. The client appointed Epsilon as their partner of choice to provide FEED, detailed design and turnkey project support following a competitive tender.

GSK required the development of a redeployed pilot-scale, high-containment granulation suite within an existing operational facility to OEB3 level of containment including an isolator around a high shear mixer. The suite needed to comply with ATEX regulations, enable low inlet-humidity operation, plus a requirement to integrate legacy equipment yet meet modern GMP and validation standards, all within tight budget and time constraints.

An undisclosed client had approval for the introduction of a new pharmaceutical compound to their site in Ireland. This required highly specialised, automated control of a multi-layer API solvent-based coating medium for a sustained release profile.

A pharmaceutical client required a safer, more precise method for solvent handling within their existing OSD coating make-up process. This involved the design and implementation of a fully ATEX-compliant, automated dispensing system that eliminated the need for PPE and ensured accurate dosing of volatile solvents within strict operator exposure limits.

A UK pharmaceutical site was transformed for pilot-scale compound development and small-batch optimisation using refurbished fluid-bed, coating and mixing equipment.

A Serbian-based pharmaceutical manufacturer faced growing demand for a generic product and needed to expand tablet coating capacity quickly. Epsilon sourced and refurbished a Manesty production coater, added a new air handler and outlet fan, and fine‑tuned the control system to meet tight budget and schedule constraints.

Epsilon supported a global pharmaceutical company with the strategic relocation of an analgesic product from Asia to Europe. The team delivered a comprehensive technical and financial feasibility report within tight timelines, enabling confident investment decisions for a £28 million programme.