Pilot-Scale 15L Fluid-Bed Drying, Tablet Coating & High-Shear Mixing System Refurbishment

GSK required the development of a redeployed pilot-scale, high-containment granulation suite within an existing operational facility to OEB3 level of containment including an isolator around a high shear mixer. The suite needed to comply with ATEX regulations, enable low inlet-humidity operation, plus a requirement to integrate legacy equipment yet meet modern GMP and validation standards, all within tight budget and time constraints.

An undisclosed client had approval for the introduction of a new pharmaceutical compound to their site in Ireland. This required highly specialised, automated control of a multi-layer API solvent-based coating medium for a sustained release profile.

A pharmaceutical client required a safer, more precise method for solvent handling within their existing OSD coating make-up process. This involved the design and implementation of a fully ATEX-compliant, automated dispensing system that eliminated the need for PPE and ensured accurate dosing of volatile solvents within strict operator exposure limits.

A UK pharmaceutical site was transformed for pilot-scale compound development and small-batch optimisation using refurbished fluid-bed, coating and mixing equipment.

A Serbian-based pharmaceutical manufacturer faced growing demand for a generic product and needed to expand tablet coating capacity quickly. Epsilon sourced and refurbished a Manesty production coater, added a new air handler and outlet fan, and fine‑tuned the control system to meet tight budget and schedule constraints.

Epsilon supported a global pharmaceutical company with the strategic relocation of an analgesic product from Asia to Europe. The team delivered a comprehensive technical and financial feasibility report within tight timelines, enabling confident investment decisions for a £28 million programme.